Publications by Current and Former Trainees

  • Kothary N, Bartos JA, Hwang GL, Dua R, Kuo WT, Hofmann LV. Computed tomography-guided percutaneous needle biopsy of indeterminate pulmonary pathology: efficacy of obtaining a diagnostic sample in immunocompetent and immunocompromised patients. Clin Lung Cancer. 2010 Jul 1;11(4):251-6. doi: 10.3816/CLC.2010.n.032. PMID: 20630827.
  • Stein W, Schrepfer S, Itoh S, Kimura N, Velotta J, Palmer O, Bartos J, Wang X, Robbins RC, Fischbein MP. Prevention of transplant coronary artery disease by prenylation inhibitors. J Heart Lung Transplant. 2011 Jul;30(7):761-9. doi: 10.1016/j.healun.2011.01.720. Epub 2011 Mar 31. PMID: 21458297.
  • Chen DR, Priest KC, Batten JN, Fragoso LE, Reinfeld BI, Laitman BM. Student Perspectives on the "Step 1 Climate" in Preclinical Medical Education. Acad Med. 2019 Mar;94(3):302-304. doi: 10.1097/ACM.0000000000002565. PMID: 30570499.
  • Batten JN, Kruse KE, Kraft SA, Fishbeyn B, Magnus DC. What Does the Word "Treatable" Mean? Implications for Communication and Decision-Making in Critical Illness. Crit Care Med. 2019 Mar;47(3):369-376. doi: 10.1097/CCM.0000000000003614. PMID: 30585833; PMCID: PMC6585940.
  • Batten JN, Blythe JA, Wieten SE, Dzeng EW. No Escalation of Treatment: Moving Beyond the Withholding/Withdrawing Debate. Am J Bioeth. 2019 Mar;19(3):63-65. doi: 10.1080/15265161.2018.1563660. PMID: 31543041.
  • Chen SF, Deitz J, Batten JN, DeCoste-Lopez J, Adam M, Alspaugh JA, Amieva MR, Becker P, Boslett B, Carline J, Chin-Hong P, Engle DL, Hayward KN, Nevins A, Porwal A, Pottinger PS, Schwartz BS, Smith S, Sow M, Teherani A, Prober CG. A Multi-Institution Collaboration to Define Core Content and Design Flexible Curricular Components for a Foundational Medical School Course: Implications for National Curriculum Reform. Acad Med. 2019 Jun;94(6):819-825. doi: 10.1097/ACM.0000000000002663. PMID: 30801270; PMCID: PMC7282480.
  • Blythe JA, Batten JN, Magnus DC. "Not Shared" Need Not Mean "Not Patient Centered": Deciding That a Patient Is Not a Candidate. JAMA Intern Med. 2019 Jun 1;179(6):851-852. doi: 10.1001/jamainternmed.2019.1227. PMID: 31157845.
  • Blythe JA, Wieten SE, Batten JN. Response to "Will We Code for Default ECMO?": Clarifying the Scope of Do-Not-ECMO Orders. AMA J Ethics. 2019 Oct 1;21(10):E926-929. doi: 10.1001/amajethics.2019.926. PMID: 31651394.
  • Rosenwohl-Mack S, Dohan D, Matthews T, Batten JN, Dzeng E. How individual ethical frameworks shape physician trainees' experiences providing end-of-life care: a qualitative study. J Med Ethics. 2021 Feb 16:10.1136/medethics-2020-106690. doi: 10.1136/medethics-2020-106690. Epub ahead of print. PMID: 33593875.
  • Wong BO, Batten JN, Blythe JA, Magnus DC. More than Conveying Information: Informed Consent as Speech Act. Am J Bioeth. 2021 May;21(5):1-3. doi: 10.1080/15265161.2021.1912513. PMID: 33945426.
  • Wong BO, Blythe JA, Batten JN, Turner BE, Lau JN, Hosamani P, Hanks WF, Magnus D. Recognizing the Role of Language in the Hidden Curriculum of Undergraduate Medical Education: Implications for Equity in Medical Training. Acad Med. 2021 Jun 1;96(6):842-847. doi: 10.1097/ACM.0000000000003657. PMID: 32769473.
  • Nichol AA, Batten JN, Halley MC, Axelrod JK, Sankar PL, Cho MK. A Typology of Existing Machine Learning-Based Predictive Analytic Tools Focused on Reducing Costs and Improving Quality in Health Care: Systematic Search and Content Analysis. J Med Internet Res. 2021 Jun 22;23(6):e26391. doi: 10.2196/26391. PMID: 34156338; PMCID: PMC8277386.
  • Rosenwohl-Mack S, Dohan D, Matthews T, Batten JN, Dzeng E. Understanding Experiences of Moral Distress in End-of-Life Care Among US and UK Physician Trainees: a Comparative Qualitative Study. J Gen Intern Med. 2021 Jul;36(7):1890-1897. doi: 10.1007/s11606-020-06314-y. Epub 2020 Oct 27. PMID: 33111237; PMCID: PMC7592132.
  • Batten JN, Blythe JA, Wieten S, Cotler MP, Kayser JB, Porter-Williamson K, Harman S, Dzeng E, Magnus D. Variation in the design of Do Not Resuscitate orders and other code status options: a multi-institutional qualitative study. BMJ Qual Saf. 2021 Aug;30(8):668-677. doi: 10.1136/bmjqs-2020-011222. Epub 2020 Oct 20. PMID: 33082165.
  • Stein SW, Batten JN, Wong BO, Clapp JT. Time Is Short, Social Relations Are Complex: Bioethics as Typology Industry. Am J Bioeth. 2022 Jun;22(6):1-3. doi: 10.1080/15265161.2022.2071070. PMID: 35616961.
  • Wong BO, Blythe JA, Wu A, Batten JN, Kennedy KM, Kouaho AS, Wren SM. Exploration of Clinician Perspectives on Multidisciplinary Tumor Board Function Beyond Clinical Decision-making. JAMA Oncol. 2022 Aug 1;8(8):1210-1212. doi: 10.1001/jamaoncol.2022.1763. PMID: 35653129; PMCID: PMC9164116.
  • Batten JN, Blythe JA, Wieten SE, Dzeng E, Kruse KE, Cotler MP, Porter-Williamson K, Kayser JB, Harman SM, Magnus D. "No Escalation of Treatment" Designations: A Multi-institutional Exploratory Qualitative Study. Chest. 2023 Jan;163(1):192-201. doi: 10.1016/j.chest.2022.08.2211. Epub 2022 Aug 23. PMID: 36007596; PMCID: PMC9993335.
  • Batten JN, O'Meeghan R, Catarino PA, Nurok M, Cotler MP. Changing the Focus in the Donation After Circulatory Death Debates. Am J Bioeth. 2023 Feb;23(2):48-49. doi: 10.1080/15265161.2022.2159094. PMID: 36681907.
  • Batten JN, Caruso P, Metaxa V. More than patient benefit: taking a broader view of ICU admission decisions. Intensive Care Med. 2023 May;49(5):556-558. doi: 10.1007/s00134-023-07074-z. Epub 2023 May 5. PMID: 37145141.
  • Batten JN, Dzeng E, Finder S, Blythe JA, Nurok M. When Critically Ill Patients with Decision Making Capacity and No Further Therapeutic Options Request Indefinite Life Support. Am J Bioeth. 2023 Jun;23(6):21-23. doi: 10.1080/15265161.2023.2201208. PMID: 37220368.
  • Shearer E, Blythe J, Magnus D, Batten JN. Recognizing choice architecture in the design of hospital code status orders. Resuscitation. 2023 Jul;188:109824. doi: 10.1016/j.resuscitation.2023.109824. Epub 2023 May 9. PMID: 37169274.
  • Dzeng E, Batten JN, Dohan D, Blythe J, Ritchie CS, Curtis JR. Hospital Culture and Intensity of End-of-Life Care at 3 Academic Medical Centers. JAMA Intern Med. 2023 Aug 1;183(8):839-848. doi: 10.1001/jamainternmed.2023.2450. PMID: 37399038; PMCID: PMC10318547.
  • Silverman A, Batten J, Berkman E, Fitzgerald H, Epstein B, Shearer E, Diekema D, Burgart A. Resuscitate but not Intubate? Partial Codes in Pediatrics. Pediatrics. 2023 Aug 1;152(2):10.1542/peds.2022-058931. doi: 10.1542/peds.2022-058931. PMID: 37435669.
  • Mittal V, Hakes NA, Magnus D, Batten JN. Vagueness in Goals-of-Care Conferences for Critically Ill Patients: Types of Hedge Language Used by Physicians. Crit Care Med. 2023 Nov 1;51(11):1538-1546. doi: 10.1097/CCM.0000000000005974. Epub 2023 Jun 26. PMID: 37358354.
  • Hakes NA, Mittal V, Magnus DC, Batten JN. The authors reply. Crit Care Med. 2023 Dec 1;51(12):e278-e279. doi: 10.1097/CCM.0000000000006059. Epub 2023 Nov 16. PMID: 37971348.
  • Ablain J, Xu M, Rothschild H, Jordan RC, Mito JK, Daniels BH, Bell CF, Joseph NM, Wu H, Bastian BC, Zon LI, Yeh I. Human tumor genomics and zebrafish modeling identify loss as a driver of mucosal melanoma. Science. 2018 Nov 30;362(6418):1055-1060. doi: 10.1126/science.aau6509. Epub 2018 Nov 1. PMID: 30385465; PMCID: PMC6475924.
  • Ho VV, O'Sullivan JW, Collins WJ, Ozdalga E, Bell CF, Shah ND, Krishnam MS, Ozawa MG, Witteles RM. Constrictive Pericarditis Revealing Rare Case of ALH Amyloidosis With Underlying Lymphoplasmacytic Lymphoma (Waldenstrom Macroglobulinemia). JACC Case Rep. 2022 Mar 2;4(5):271-275. doi: 10.1016/j.jaccas.2022.01.007. PMID: 35257101; PMCID: PMC8897150.
  • Gao H, Baylis RA, Luo L, Kojima Y, Bell CF, Ross EG, Wang F, Leeper NJ. Clustering cancers by shared transcriptional risk reveals novel targets for cancer therapy. Mol Cancer. 2022 May 18;21(1):116. doi: 10.1186/s12943-022-01592-y. PMID: 35585548; PMCID: PMC9115915.
  • Bell CF, Lei X, Haas A, Baylis RA, Gao H, Luo L, Giordano SH, Wehner MR, Nead KT, Leeper NJ. Risk of Cancer After Diagnosis of Cardiovascular Disease. JACC CardioOncol. 2023 Apr 11;5(4):431-440. doi: 10.1016/j.jaccao.2023.01.010. PMID: 37614573; PMCID: PMC10443115.
  • Baylis RA, Gao H, Wang F, Bell CF, Luo L, Bjorkegren JLM, Leeper NJ. Identifying shared transcriptional risk patterns between atherosclerosis and cancer. iScience. 2023 Jul 29;26(9):107513. doi: 10.1016/j.isci.2023.107513. PMID: 37636064; PMCID: PMC10448075.
  • Schneider MK, Wang J, Kare A, Adkar SS, Salmi D, Bell CF, Alsaigh T, Wagh D, Coller J, Mayer A, Snyder SJ, Borowsky AD, Long SR, Lansberg MG, Steinberg GK, Heit JJ, Leeper NJ, Ferrara KW. Combined near infrared photoacoustic imaging and ultrasound detects vulnerable atherosclerotic plaque. Biomaterials. 2023 Nov;302:122314. doi: 10.1016/j.biomaterials.2023.122314. Epub 2023 Sep 11. PMID: 37776766; PMCID: PMC10872807.
  • Luo L, Fu C, Bell CF, Wang Y, Leeper NJ. Role of vascular smooth muscle cell clonality in atherosclerosis. Front Cardiovasc Med. 2023 Nov 28;10:1273596. doi: 10.3389/fcvm.2023.1273596. PMID: 38089777; PMCID: PMC10713728.
  • Sinnott R, Winters L, Larson B, Mytsa D, Taus P, Cappell KM, Whitehurst AW. Mechanisms promoting escape from mitotic stress-induced tumor cell death. Cancer Res. 2014 Jul 15;74(14):3857-69. doi: 10.1158/0008-5472.CAN-13-3398. Epub 2014 May 23. PMID: 24860162; PMCID: PMC4102622.
  • Cappell K, Sundaram V, Park A, Shiraz P, Gupta R, Jenkins P, Periyakoil VSJ, Muffly L. Advance Directive Utilization Is Associated with Less Aggressive End-of-Life Care in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2018 May;24(5):1035-1040. doi: 10.1016/j.bbmt.2018.01.014. Epub 2018 Jan 31. PMID: 29371107; PMCID: PMC6364975.
  • Casto AM, Henn BM, Kidd JM, Bustamante CD, Feldman MW. A tale of two haplotypes: the EDA2R/AR Intergenic region is the most divergent genomic segment between Africans and East Asians in the human genome. Hum Biol. 2012 Dec;84(6):641-94. doi: 10.3378/027.084.0604. PMID: 23959643.
  • Stack S, Nguyen DV, Casto A, Ahuja N. Diffuse alveolar damage in a patient receiving dronedarone. Chest. 2015 Apr;147(4):e131-e133. doi: 10.1378/chest.14-1849. PMID: 25846536.
  • Chan SM, George T, Cherry AM, Medeiros BC. Complete remission of primary plasma cell leukemia with bortezomib, doxorubicin, and dexamethasone: a case report. Cases J. 2009 Feb 4;2(1):121. doi: 10.1186/1757-1626-2-121. PMID: 19192311; PMCID: PMC2644294.
  • Chan SM, Majeti R. Role of DNMT3A, TET2, and IDH1/2 mutations in pre-leukemic stem cells in acute myeloid leukemia. Int J Hematol. 2013 Dec;98(6):648-57. doi: 10.1007/s12185-013-1407-8. Epub 2013 Aug 15. PMID: 23949914; PMCID: PMC5542003.
  • Chan SM, Chadwick J, Young DL, Holmes E, Gotlib J. Intensive serial biomarker profiling for the prediction of neutropenic Fever in patients with hematologic malignancies undergoing chemotherapy: a pilot study. Hematol Rep. 2014 Jun 23;6(2):5466. doi: 10.4081/hr.2014.5466. PMID: 25013718; PMCID: PMC4091290.
  • Nguyen le XT, Chan SM, Ngo TD, Raval A, Kim KK, Majeti R, Mitchell BS. Interaction of TIF-90 and filamin A in the regulation of rRNA synthesis in leukemic cells. Blood. 2014 Jul 24;124(4):579-89. doi: 10.1182/blood-2013-12-544726. Epub 2014 May 21. PMID: 24850755.
  • Sinha S, Thomas D, Yu L, Gentles AJ, Jung N, Corces-Zimmerman MR, Chan SM, Reinisch A, Feinberg AP, Dill DL, Majeti R. Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition. Blood. 2015 Jan 8;125(2):316-26. doi: 10.1182/blood-2014-03-566018. Epub 2014 Nov 14. PMID: 25398938; PMCID: PMC4287638.
  • Chan SM, Thomas D, Corces-Zimmerman MR, Xavy S, Rastogi S, Hong WJ, Zhao F, Medeiros BC, Tyvoll DA, Majeti R. Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia. Nat Med. 2015 Feb;21(2):178-84. doi: 10.1038/nm.3788. Epub 2015 Jan 19. PMID: 25599133; PMCID: PMC4406275.
  • Reinisch A, Chan SM, Thomas D, Majeti R. Biology and Clinical Relevance of Acute Myeloid Leukemia Stem Cells. Semin Hematol. 2015 Jul;52(3):150-64. doi: 10.1053/j.seminhematol.2015.03.008. Epub 2015 Mar 18. PMID: 26111462; PMCID: PMC5516648.
  • Mazumdar C, Shen Y, Xavy S, Zhao F, Reinisch A, Li R, Corces MR, Flynn RA, Buenrostro JD, Chan SM, Thomas D, Koenig JL, Hong WJ, Chang HY, Majeti R. Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation. Cell Stem Cell. 2015 Dec 3;17(6):675-688. doi: 10.1016/j.stem.2015.09.017. Epub 2015 Oct 22. PMID: 26607380; PMCID: PMC4671831.
  • Corces MR, Buenrostro JD, Wu B, Greenside PG, Chan SM, Koenig JL, Snyder MP, Pritchard JK, Kundaje A, Greenleaf WJ, Majeti R, Chang HY. Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution. Nat Genet. 2016 Oct;48(10):1193-203. doi: 10.1038/ng.3646. Epub 2016 Aug 15. PMID: 27526324; PMCID: PMC5042844.
  • Huang M, Garcia JS, Thomas D, Zhu L, Nguyen LX, Chan SM, Majeti R, Medeiros BC, Mitchell BS. Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells. Oncotarget. 2016 Nov 15;7(46):74917-74930. doi: 10.18632/oncotarget.12493. PMID: 27732946; PMCID: PMC5342712.
  • Matre P, Velez J, Jacamo R, Qi Y, Su X, Cai T, Chan SM, Lodi A, Sweeney SR, Ma H, Davis RE, Baran N, Haferlach T, Su X, Flores ER, Gonzalez D, Konoplev S, Samudio I, DiNardo C, Majeti R, Schimmer AD, Li W, Wang T, Tiziani S, Konopleva M. Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes. Oncotarget. 2016 Nov 29;7(48):79722-79735. doi: 10.18632/oncotarget.12944. PMID: 27806325; PMCID: PMC5340236.
  • Sinha S, Thomas D, Chan S, Gao Y, Brunen D, Torabi D, Reinisch A, Hernandez D, Rankin EB, Bernards R, Majeti R, Dill DL. Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data. Nat Commun. 2017 May 31;8:15580. doi: 10.1038/ncomms15580. PMID: 28561042; PMCID: PMC5460027.
  • McKeown MR, Corces MR, Eaton ML, Fiore C, Lee E, Lopez JT, Chen MW, Smith D, Chan SM, Koenig JL, Austgen K, Guenther MG, Orlando DA, Loven J, Fritz CC, Majeti R. Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist. Cancer Discov. 2017 Oct;7(10):1136-1153. doi: 10.1158/2159-8290.CD-17-0399. Epub 2017 Jul 20. PMID: 28729405; PMCID: PMC5962349.
  • Roberts LW, Chan S, Torous J. New tests, new tools: mobile and connected technologies in advancing psychiatric diagnosis. NPJ Digit Med. 2018 Feb 26;1:20176. doi: 10.1038/s41746-017-0006-0. PMID: 31304350; PMCID: PMC6550288.