• Dao V, Yuki K, Lo YH, Nakano M, Kuo CJ. Immune organoids: from tumor modeling to precision oncology. Trends Cancer. 2022 Oct;8(10):870-880. doi: 10.1016/j.trecan.2022.06.001. Epub 2022 Jun 27. PMID: 35773148; PMCID: PMC9704769.
• Dao V, Heestand G. Beyond EGFR inhibitors in advanced colorectal cancer: Targeting BRAF and HER2. Curr Probl Cancer. 2023 Aug;47(4):100960. doi: 10.1016/j.currproblcancer.2023.100960. Epub 2023 May 10. PMID: 37285606.
• Dewey FE, Kapoor JR, Williams RS, Lipinski MJ, Ashley EA, Hadley D, Myers J, Froelicher VF. Ventricular arrhythmias during clinical treadmill testing and prognosis. Arch Intern Med. 2008 Jan 28;168(2):225-34. doi: 10.1001/archinte.168.2.225. PMID: 18227372.
• Dewey FE, Rosenthal D, Murphy DJ, Froelicher VF, Ashley EA. Does size matter? Clinical applications of scaling cardiac size and function for body size. Circulation. 2008 Apr 29;117(17):2279-87. doi: 10.1161/CIRCULATIONAHA.107.736785. PMID: 18443249.
• Rafie AH, Dewey FE, Myers J, Froelicher VF. Age-adjusted modification of the Duke Treadmill Score nomogram. Am Heart J. 2008 Jun;155(6):1033-8. doi: 10.1016/j.ahj.2008.01.025. Epub 2008 Mar 12. PMID: 18513516.
• Sadrzadeh Rafie AH, Sungar GW, Dewey FE, Hadley D, Myers J, Froelicher VF. Prognostic value of double product reserve. Eur J Cardiovasc Prev Rehabil. 2008 Oct;15(5):541-7. doi: 10.1097/HJR.0b013e328305deef. PMID: 18665099.
• Sadrzadeh Rafie AH, Dewey FE, Sungar GW, Ashley EA, Hadley D, Myers J, Froelicher VF. Age and double product (systolic blood pressure x heart rate) reserve-adjusted modification of the Duke Treadmill Score nomogram in men. Am J Cardiol. 2008 Nov 15;102(10):1407-12. doi: 10.1016/j.amjcard.2008.07.020. Epub 2008 Sep 11. PMID: 18993164.
• Perez MV, Dewey FE, Tan SY, Myers J, Froelicher VF. Added value of a resting ECG neural network that predicts cardiovascular mortality. Ann Noninvasive Electrocardiol. 2009 Jan;14(1):26-34. doi: 10.1111/j.1542-474X.2008.00270.x. PMID: 19149790; PMCID: PMC6932462.
• Dewey FE, Perez M, Hadley D, Freeman JV, Wang P, Ashley EA, Myers J, Froelicher VF. Statin use and ventricular arrhythmias during clinical treadmill testing. J Cardiovasc Electrophysiol. 2009 Feb;20(2):193-9. doi: 10.1111/j.1540-8167.2008.01284.x. Epub 2008 Sep 3. PMID: 18775041.
• Perez MV, Dewey FE, Marcus R, Ashley EA, Al-Ahmad AA, Wang PJ, Froelicher VF. Electrocardiographic predictors of atrial fibrillation. Am Heart J. 2009 Oct;158(4):622-8. doi: 10.1016/j.ahj.2009.08.002. PMID: 19781423.
• Lipinski MJ, Dewey FE, Biondi-Zoccai GG, Abbate A, Vetrovec GW, Froelicher VF. Hemoglobin levels predict exercise performance, ST-segment depression, and outcome in patients referred for routine exercise treadmill testing. Clin Cardiol. 2009 Dec;32(12):E22-31. doi: 10.1002/clc.20418. PMID: 20014211; PMCID: PMC6652827.
• Le VV, Wheeler MT, Mandic S, Dewey F, Fonda H, Perez M, Sungar G, Garza D, Ashley EA, Matheson G, Froelicher V. Addition of the electrocardiogram to the preparticipation examination of college athletes. Clin J Sport Med. 2010 Mar;20(2):98-105. doi: 10.1097/JSM.0b013e3181d44705. PMID: 20215891.
• Ashley EA, Butte AJ, Wheeler MT, Chen R, Klein TE, Dewey FE, Dudley JT, Ormond KE, Pavlovic A, Morgan AA, Pushkarev D, Neff NF, Hudgins L, Gong L, Hodges LM, Berlin DS, Thorn CF, Sangkuhl K, Hebert JM, Woon M, Sagreiya H, Whaley R, Knowles JW, Chou MF, Thakuria JV, Rosenbaum AM, Zaranek AW, Church GM, Greely HT, et al. Clinical assessment incorporating a personal genome. Lancet. 2010 May 1;375(9725):1525-35. doi: 10.1016/S0140-6736(10)60452-7. PMID: 20435227; PMCID: PMC2937184.
• Dewey FE, Perez MV, Wheeler MT, Watt C, Spin J, Langfelder P, Horvath S, Hannenhalli S, Cappola TP, Ashley EA. Gene coexpression network topology of cardiac development, hypertrophy, and failure. Circ Cardiovasc Genet. 2011 Feb;4(1):26-35. doi: 10.1161/CIRCGENETICS.110.941757. Epub 2010 Dec 2. PMID: 21127201; PMCID: PMC3324316.
• Dewey FE, Wheeler MT, Ashley EA. Systems biology of heart failure, challenges and hopes. Curr Opin Cardiol. 2011 Jul;26(4):314-21. doi: 10.1097/HCO.0b013e328346597d. PMID: 21478745.
• Uberoi A, Stein R, Perez MV, Freeman J, Wheeler M, Dewey F, Peidro R, Hadley D, Drezner J, Sharma S, Pelliccia A, Corrado D, Niebauer J, Estes NA, Ashley E, Froelicher V. Interpretation of the electrocardiogram of young athletes. Circulation. 2011 Aug 9;124(6):746-57. doi: 10.1161/CIRCULATIONAHA.110.013078. PMID: 21824936.
• Dewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, Cornejo OE, Knowles JW, Woon M, Sangkuhl K, Gong L, Thorn CF, Hebert JM, Capriotti E, David SP, Pavlovic A, West A, Thakuria JV, Ball MP, Zaranek AW, Rehm HL, Church GM, West JS, Bustamante CD, Snyder M, et al. Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. PLoS Genet. 2011 Sep;7(9):e1002280. doi: 10.1371/journal.pgen.1002280. Epub 2011 Sep 15. PMID: 21935354; PMCID: PMC3174201.
• Lam HY, Clark MJ, Chen R, Chen R, Natsoulis G, O'Huallachain M, Dewey FE, Habegger L, Ashley EA, Gerstein MB, Butte AJ, Ji HP, Snyder M. Performance comparison of whole-genome sequencing platforms. Nat Biotechnol. 2011 Dec 18;30(1):78-82. doi: 10.1038/nbt.2065. PMID: 22178993; PMCID: PMC4076012.
• Dewey FE, Pan S, Wheeler MT, Quake SR, Ashley EA. DNA sequencing: clinical applications of new DNA sequencing technologies. Circulation. 2012 Feb 21;125(7):931-44. doi: 10.1161/CIRCULATIONAHA.110.972828. PMID: 22354974; PMCID: PMC3364518.
• Chen R, Mias GI, Li-Pook-Than J, Jiang L, Lam HY, Chen R, Miriami E, Karczewski KJ, Hariharan M, Dewey FE, Cheng Y, Clark MJ, Im H, Habegger L, Balasubramanian S, O'Huallachain M, Dudley JT, Hillenmeyer S, Haraksingh R, Sharon D, Euskirchen G, Lacroute P, Bettinger K, Boyle AP, Kasowski M, Grubert F, Seki S, Garcia M, Whirl-Carrillo M, et al. Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell. 2012 Mar 16;148(6):1293-307. doi: 10.1016/j.cell.2012.02.009. PMID: 22424236; PMCID: PMC3341616.
• Dewey FE, Grove ME, Pan C, Goldstein BA, Bernstein JA, Chaib H, Merker JD, Goldfeder RL, Enns GM, David SP, Pakdaman N, Ormond KE, Caleshu C, Kingham K, Klein TE, Whirl-Carrillo M, Sakamoto K, Wheeler MT, Butte AJ, Ford JM, Boxer L, Ioannidis JP, Yeung AC, Altman RB, Assimes TL, Snyder M, Ashley EA, Quertermous T. Clinical interpretation and implications of whole-genome sequencing. JAMA. 2014 Mar 12;311(10):1035-45. doi: 10.1001/jama.2014.1717. PMID: 24618965; PMCID: PMC4119063.
• Dewey F, Ashley E, Quertermous T. Interpreting whole-genome sequencing--reply. JAMA. 2014 Jul 16;312(3):296-7. doi: 10.1001/jama.2014.6605. PMID: 25027152.
• Priest JR, Ceresnak SR, Dewey FE, Malloy-Walton LE, Dunn K, Grove ME, Perez MV, Maeda K, Dubin AM, Ashley EA. Molecular diagnosis of long QT syndrome at 10 days of life by rapid whole genome sequencing. Heart Rhythm. 2014 Oct;11(10):1707-13. doi: 10.1016/j.hrthm.2014.06.030. Epub 2014 Jun 25. PMID: 24973560; PMCID: PMC4379486.
• Dewey FE, Grove ME, Priest JR, Waggott D, Batra P, Miller CL, Wheeler M, Zia A, Pan C, Karzcewski KJ, Miyake C, Whirl-Carrillo M, Klein TE, Datta S, Altman RB, Snyder M, Quertermous T, Ashley EA. Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data. PLoS Genet. 2015 Oct 8;11(10):e1005496. doi: 10.1371/journal.pgen.1005496. PMID: 26448358; PMCID: PMC4598191.
• Perez MV, Pavlovic A, Shang C, Wheeler MT, Miller CL, Liu J, Dewey FE, Pan S, Thanaporn PK, Absher D, Brandimarto J, Salisbury H, Chan K, Mukherjee R, Konadhode RP, Myers RM, Sedehi D, Scammell TE, Quertermous T, Cappola T, Ashley EA. Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure. J Am Coll Cardiol. 2015 Dec 8;66(22):2522-33. doi: 10.1016/j.jacc.2015.09.061. PMID: 26653627; PMCID: PMC8991813.
• Homburger JR, Green EM, Caleshu C, Sunitha MS, Taylor RE, Ruppel KM, Metpally RP, Colan SD, Michels M, Day SM, Olivotto I, Bustamante CD, Dewey FE, Ho CY, Spudich JA, Ashley EA. Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation. Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):6701-6. doi: 10.1073/pnas.1606950113. Epub 2016 May 31. PMID: 27247418; PMCID: PMC4914177.
• Priest JR, Gawad C, Kahlig KM, Yu JK, O'Hara T, Boyle PM, Rajamani S, Clark MJ, Garcia ST, Ceresnak S, Harris J, Boyle S, Dewey FE, Malloy-Walton L, Dunn K, Grove M, Perez MV, Neff NF, Chen R, Maeda K, Dubin A, Belardinelli L, West J, Antolik C, Macaya D, Quertermous T, Trayanova NA, Quake SR, Ashley EA. Early somatic mosaicism is a rare cause of long-QT syndrome. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11555-11560. doi: 10.1073/pnas.1607187113. Epub 2016 Sep 28. PMID: 27681629; PMCID: PMC5068256.
• Nielsen JB, Fritsche LG, Zhou W, Teslovich TM, Holmen OL, Gustafsson S, Gabrielsen ME, Schmidt EM, Beaumont R, Wolford BN, Lin M, Brummett CM, Preuss MH, Refsgaard L, Bottinger EP, Graham SE, Surakka I, Chu Y, Skogholt AH, Dalen H, Boyle AP, Oral H, Herron TJ, Kitzman J, Jalife J, Svendsen JH, Olesen MS, Njølstad I, Løchen ML,... Dewey FE, et al. Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development. Am J Hum Genet. 2018 Jan 4;102(1):103-115. doi: 10.1016/j.ajhg.2017.12.003. Epub 2017 Dec 28. PMID: 29290336; PMCID: PMC5777936.
• Klarin D, Damrauer SM, Cho K, Sun YV, Teslovich TM, Honerlaw J, Gagnon DR, DuVall SL, Li J, Peloso GM, Chaffin M, Small AM, Huang J, Tang H, Lynch JA, Ho YL, Liu DJ, Emdin CA, Li AH, Huffman JE, Lee JS, Natarajan P, Chowdhury R, Saleheen D, Vujkovic M, Baras A, Pyarajan S, Di Angelantonio E, Neale BM,... Dewey FE, et al. Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. Nat Genet. 2018 Nov;50(11):1514-1523. doi: 10.1038/s41588-018-0222-9. Epub 2018 Oct 1. PMID: 30275531; PMCID: PMC6521726.
• Cordero P, Parikh VN, Chin ET, Erbilgin A, Gloudemans MJ, Shang C, Huang Y, Chang AC, Smith KS, Dewey F, Zaleta K, Morley M, Brandimarto J, Glazer N, Waggott D, Pavlovic A, Zhao M, Moravec CS, Tang WHW, Skreen J, Malloy C, Hannenhalli S, Li H, Ritter S, Li M, Bernstein D, Connolly A, Hakonarson H, Lusis AJ, et al. Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure. Nat Commun. 2019 Jun 24;10(1):2760. doi: 10.1038/s41467-019-10591-5. PMID: 31235787; PMCID: PMC6591478.
• De Jong HN, Dewey FE, Cordero P, Victorio RA, Kirillova A, Huang Y, Madhvani R, Seo K, Werdich AA, Lan F, Orcholski M, Liu WR, Erbilgin A, Wheeler MT, Chen R, Pan S, Kim YM, Bommakanti K, Marcou CA, Bos JM, Haddad F, Ackerman M, Vasan RS, MacRae C, Wu JC, de Jesus Perez V, Snyder M, Parikh VN, Ashley EA. Wnt Signaling Interactor WTIP (Wilms Tumor Interacting Protein) Underlies Novel Mechanism for Cardiac Hypertrophy. Circ Genom Precis Med. 2022 Aug;15(4):e003563. doi: 10.1161/CIRCGEN.121.003563. Epub 2022 Jun 7. PMID: 35671065; PMCID: PMC10445530.
• Elezaby A, Parikh VN, Nayor M. Iron Deficiency as a Potential Modulator of Subclinical Deficiencies in Cardiac Performance and Exercise Capacity. J Card Fail. 2021 Jul;27(7):822-824. doi: 10.1016/j.cardfail.2021.04.018. PMID: 34246431.
• Qvit N, Lin AJ, Elezaby A, Ostberg NP, Campos JC, Ferreira JCB, Mochly-Rosen D. A Selective Inhibitor of Cardiac Troponin I Phosphorylation by Delta Protein Kinase C (δPKC) as a Treatment for Ischemia-Reperfusion Injury. Pharmaceuticals (Basel). 2022 Feb 22;15(3):10.3390/ph15030271. doi: 10.3390/ph15030271. PMID: 35337069; PMCID: PMC8950820.
• Elezaby A, Dexheimer R, Sallam K. Cardiovascular effects of immunosuppression agents. Front Cardiovasc Med. 2022 Sep 21;9:981838. doi: 10.3389/fcvm.2022.981838. PMID: 36211586; PMCID: PMC9534182.
• Vijayan V, Yan H, Lohmeyer JK, Prentiss KA, Patil RV, Barbarito G, Lopez I, Elezaby A, Peterson K, Baker J, Ostberg NP, Bertaina A, Negrin RS, Mochly-Rosen D, Weinberg KI, Haileselassie B. Extracellular release of mitochondria induced by pre-hematopoietic stem cell transplant conditioning exacerbates GVHD. Blood Adv. 2024 May 3:10.1182/bloodadvances.2023012328. doi: 10.1182/bloodadvances.2023012328. Epub ahead of print. PMID: 38701354.
• Yau VM, Schiff KC, Arnold BF, Griffith JF, Gruber JS, Wright CC, Wade TJ, Burns S, Hayes JM, McGee C, Gold M, Cao Y, Boehm AB, Weisberg SB, Colford JM. Effect of submarine groundwater discharge on bacterial indicators and swimmer health at Avalon Beach, CA, USA. Water Res. 2014 Aug 1;59:23-36. doi: 10.1016/j.watres.2014.03.050. Epub 2014 Mar 29. PMID: 24776951.
• Gruber JJ, Colevas AD. Differentiated thyroid cancer: focus on emerging treatments for radioactive iodine-refractory patients. Oncologist. 2015 Feb;20(2):113-26. doi: 10.1634/theoncologist.2014-0313. Epub 2015 Jan 23. PMID: 25616432; PMCID: PMC4319630.
• Reza Sailani M, Jahanbani F, Nasiri J, Behnam M, Salehi M, Sedghi M, Hoseinzadeh M, Takahashi S, Zia A, Gruber J, Lynch JL, Lam D, Winkelmann J, Amirkiai S, Pang B, Rego S, Mazroui S, Bernstein JA, Snyder MP. Association of AHSG with alopecia and mental retardation (APMR) syndrome. Hum Genet. 2017 Mar;136(3):287-296. doi: 10.1007/s00439-016-1756-5. Epub 2017 Jan 4. PMID: 28054173.
• Gruber JJ, Telli ML. Outstanding Questions in the Clinical Management of Triple-Negative Breast Cancer. J Oncol Pract. 2017 May;13(5):305-307. doi: 10.1200/JOP.2017.023341. PMID: 28489983.
• Liu Q, Van Bortle K, Zhang Y, Zhao MT, Zhang JZ, Geller BS, Gruber JJ, Jiang C, Wu JC, Snyder MP. Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid. Sci Rep. 2018 Aug 28;8(1):12960. doi: 10.1038/s41598-018-31192-0. PMID: 30154523; PMCID: PMC6113333.
• Gruber JJ, Chen J, Geller B, Jager N, Lipchik AM, Wang G, Kurian AW, Ford JM, Snyder MP. Chromatin Remodeling in Response to BRCA2-Crisis. Cell Rep. 2019 Aug 20;28(8):2182-2193.e6. doi: 10.1016/j.celrep.2019.07.057. PMID: 31433991; PMCID: PMC6754178.
• Gruber JJ, Geller B, Lipchik AM, Chen J, Salahudeen AA, Ram AN, Ford JM, Kuo CJ, Snyder MP. HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding. Mol Cell. 2019 Aug 22;75(4):711-724.e5. doi: 10.1016/j.molcel.2019.05.034. Epub 2019 Jul 2. PMID: 31278053; PMCID: PMC6707831.
• Chen J, Haanpaa MK, Gruber JJ, Jager N, Ford JM, Snyder MP. High-Resolution Bisulfite-Sequencing of Peripheral Blood DNA Methylation in Early-Onset and Familial Risk Breast Cancer Patients. Clin Cancer Res. 2019 Sep 1;25(17):5301-5314. doi: 10.1158/1078-0432.CCR-18-2423. Epub 2019 Jun 7. PMID: 31175093; PMCID: PMC6726519.
• Stowers RS, Shcherbina A, Israeli J, Gruber JJ, Chang J, Nam S, Rabiee A, Teruel MN, Snyder MP, Kundaje A, Chaudhuri O. Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility. Nat Biomed Eng. 2019 Dec;3(12):1009-1019. doi: 10.1038/s41551-019-0420-5. Epub 2019 Jul 8. PMID: 31285581; PMCID: PMC6899165.
• Li Y, Gruber JJ, Litzenburger UM, Zhou Y, Miao YR, LaGory EL, Li AM, Hu Z, Yip M, Hart LS, Maris JM, Chang HY, Giaccia AJ, Ye J. Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia. Cell Death Dis. 2020 Feb 6;11(2):102. doi: 10.1038/s41419-020-2303-9. PMID: 32029721; PMCID: PMC7005271.
• Telli ML, Chu C, Badve SS, Vinayak S, Silver DP, Isakoff SJ, Kaklamani V, Gradishar W, Stearns V, Connolly RM, Ford JM, Gruber JJ, Adams S, Garber J, Tung N, Neff C, Bernhisel R, Timms KM, Richardson AL. Association of Tumor-Infiltrating Lymphocytes with Homologous Recombination Deficiency and Status in Patients with Early Triple-Negative Breast Cancer: A Pooled Analysis. Clin Cancer Res. 2020 Jun 1;26(11):2704-2710. doi: 10.1158/1078-0432.CCR-19-0664. Epub 2019 Dec 3. PMID: 31796517.
• Al-Mousily MF, Lopez L, Muniz JC, Sasaki N, Seltzer I, Gruber J, Welch E. Aortic size in children: Systolic measurements are different from diastolic measurements. Ann Pediatr Cardiol. 2021 ;14(2):165-169. doi: 10.4103/apc.APC_157_19. Epub 2021 Mar 26. PMID: 34103855; PMCID: PMC8174627.
• Sanghi A, Gruber JJ, Metwally A, Jiang L, Reynolds W, Sunwoo J, Orloff L, Chang HY, Kasowski M, Snyder MP. Chromatin accessibility associates with protein-RNA correlation in human cancer. Nat Commun. 2021 Sep 30;12(1):5732. doi: 10.1038/s41467-021-25872-1. PMID: 34593797; PMCID: PMC8484618.
• Thakkar D, Paliwal S, Dharmadhikari B, Guan S, Liu L, Kar S, Tulsian NK, Gruber JJ, DiMascio L, Paszkiewicz KH, Ingram PJ, D Boyd-Kirkup J. Rationally targeted anti-VISTA antibody that blockades the C-C' loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit tumor growth in an Fc independent manner. J Immunother Cancer. 2022 Feb;10(2):10.1136/jitc-2021-003382. doi: 10.1136/jitc-2021-003382. PMID: 35131861; PMCID: PMC8823246.
• Gruber JJ, Afghahi A, Timms K, DeWees A, Gross W, Aushev VN, Wu HT, Balcioglu M, Sethi H, Scott D, Foran J, McMillan A, Ford JM, Telli ML. A phase II study of talazoparib monotherapy in patients with wild-type BRCA1 and BRCA2 with a mutation in other homologous recombination genes. Nat Cancer. 2022 Oct;3(10):1181-1191. doi: 10.1038/s43018-022-00439-1. Epub 2022 Oct 17. PMID: 36253484; PMCID: PMC9586861.